Travis Bickle's problems in order of severity are:
mental unstability, purposelessness, ignorance.
These are the defining traits of toxicity of a character, toxic masculinity in Travis's case.
A go-to template of a spectrum for disturbed male characters that starts from Michael Scott on one end and ends with Patrick Bateman on the other end.
Probably the greatest character study of all time.
***
Joker, American Psycho, even American Beauty all borrow (steal?) a lot from this movie and they are still amazing movies on their own.
God, 70s was really the decade for masterpieces, wasn't it?